What is Acne?
Acne is a disease of the pilosebaceous unit that can affect males and females of all ethnicities. The four main pathogenic factors include: excess sebum production, inflammation, P. acnes bacteria, and follicular hyperproliferation. This can lead to post inflammatory hyperpigmentation, scarring, and psychologic distress.
Treatment
There are several kinds of topical, oral, and procedural treatments for acne. Each are targeted towards the four pathogenic factors. Common treatment modalities include:
Follicular hyperproliferation – topical retinoids, oral isotretinoin, azelaic acid, salicylic acid
Sebum production – oral isotretinoin, oral contraceptives, spironolactone, clascoterone
P. acnes bacteria – benzoyl peroxide, topical and oral antibiotics, azelaic acid
Inflammation – oral isotretinoin, oral tetracyclines, topical retinoid, azelaic acid, topical dapsone
Skincare
It is important to encourage the use of gentle cleansers. Patients need to avoid harsh scrubbing of the skin as this can aggravate inflammatory acne and lead to more breakouts. Using “noncomedogenic” products can be beneficial, however this labeling is not regulated. Encourage patients not to pick at lesions. This can lead to increased scarring.
Expectations
It is important to discuss with patients that it generally takes two to three months of consistent use of an acne regimen to assess the initial response to treatment. Without this discussion, there is risk of early discontinuation of treatment by the patient. Secondly, it is important to notify patients that acne treatments are suppressive, not curative, so long-term maintenance therapy is often needed.
Written by Sara Doherty, APRN





Una explicación clara sobre la lotería nacional puede ayudar bastante a los lectores. Además de mostrar resultados, es recomendable mantener las fechas actualizadas y utilizar información procedente de fuentes confiables.
This is a really clear and informative breakdown of what acne actually is and why it happens. Dealing with skin issues can be super frustrating, especially when trying to figure out the right skincare routine. Honestly, after spending way too much time researching health and skincare tips online, my brain always needs a little break. Whenever I need a quick mental breather, I usually hop on minigame to unwind for a few minutes. Thanks for sharing this helpful guide!
Great effort in creating this post. Thank you for sharing your valuable knowledge.
Mumbai Isabasu
L'acné est vraiment un sujet complexe, et l'accent mis sur l'inflammation dans cet article est crucial. J'ai souvent remarqué que choisir des produits non comédogènes aide ma peau à rester plus claire. Pour ceux qui cherchent à approfondir certains aspects de la santé cutanée, le site Abyssus propose des conseils pratiques sur divers sujets liés à la gestion de la peau et du bien-être.
C'est fascinant de voir comment l'inflammation joue un rôle clé dans l'acné. J'ai personnellement constaté que l'utilisation de nettoyants doux, comme recommandé dans l'article, a vraiment amélioré l'état de ma peau. Pour ceux qui s'intéressent à des stratégies complémentaires pour le bien-être, le site Decaying Winter Wiki offre des conseils sur la gestion de divers aspects de la santé et du bien-être.