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Acne: An Inflammatory Disorder

May 25, 2022
2 min read

Causes

Acne typically begins in the pre-pubertal years, extending into adolescence and early adulthood. Increased levels of androgens cause increased sebum production, abnormal follicular keratinization, colonization of the bacterium P. acnes, and inflammation. This results in clogged pores such as open comedones (blackheads), closed comedones (whiteheads), papules, pustules, and in more severe cases, nodules. Acne is frequently found on the face, neck, chest, and back. Some women experience hormonal acne in their 20’s, 30’s and even 40’s, which usually flares on the chin, jawline, and neck.


Complications

Individuals with moderate-to-severe acne may develop scarring. This can negatively affect one’s self esteem or body satisfaction. It is best to wait at least 8 months after treatment is finished to determine the extent of severity. Scarring can be treated with topical retinoids, microneedling, and chemical peels.


Post-inflammatory hyperpigmentation is also referred to as “pseudo scarring.” This occurs when there is discoloration to the skin after the acne has healed. This may fade in time and is treated similarly to acne scarring if it does not fully resolve on its own.


Treatments

At home treatments include choosing a facial cleanser and moisturizer to use daily that are noncomedogenic. It is also important to avoid picking at breakouts to prevent scarring.


Prescription treatments depend on the nature and severity of one’s acne. Topical treatments include retinoids, antibiotics, benzoyl peroxide, sulfur, sodium sulfacetamide, salicylic acid, and azelaic acid. Oral treatments include antibiotics, spironolactone, and isotretinoin. Some larger cystic lesions can even be treated with intralesional steroidal injections.


Maskne

With the constant wearing of face masks, there has been an increase in patients reporting acne on their nose, cheeks, and chin. Cotton masks may be less irritating than disposable masks. However, they can harbor oil and bacteria, so only use cotton masks if you are able to wash them after each daily use. Keep a simple skin care routine rather than adding in spot treatments that can potentially irritate skin more and limit use of makeup.





19 Comments


This is a helpful reminder that acne is more than just a surface-level skin concern, and understanding its inflammatory nature can help people make better skincare decisions. I think sharing clear information about skin conditions is important because it encourages people to seek appropriate advice instead of relying on myths or harsh treatments. Everyone’s skin is different, so learning about the underlying causes can make a real difference. For a fun change of pace, check out Geometry Dash and put your reflexes to the test with its challenging levels and energetic soundtrack!

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It's useful to clarify that post-inflammatory hyperpigmentation is just temporary discoloration rather than true scarring, since this explains why it can fade naturally over time without intervention.

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© 2023 Kansas Medical Clinic, PA ​ - If you have a medical emergency, please call 911.  All information provided herein is for educational purposes only. If you have a medical condition, please consult a physician to get a proper diagnosis and treatment plan.

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